Antibiotics resistance is widespread and increasing worldwide. Resistance to antibiotics made the necessity to develop newer antibiotics to overcome the resistance. Isolation, characterization, bioprocessing and product evaluation of the soil isolates which was given the name ABF-1. Microscopical studies, Microbial sensitivity testing using different strains of bacteria and fungi, taxonomic studies, morphological and cultural characteristic in various ISP ( International Streptomyces Project), Carbohydrates assimilation test, bioprocessing for antibiotic production, antibiotic recovery by solvent extraction, Identification of Antibiotics by thin layer chromatography, biological activity such as antimicrobial and Cytotoxicity were performed. N- Butanol extract showed antimicrobial activity against, E.coli, Bacillus subtilis, staphylococcus aureus. Ethyl acetate extract showed antimicrobial activity against E.coli, pseudomonas auroginosa, Bacillus subtilis, Staphylococcus aureus, Aspergillus niger, Aspergillus flavus, Candida albicans, Candida krusei. The methanolic extract showed antimicrobial activity against Escheria coli, Bacillus subtilis, Staphylococcus aureus, Aspergillus flavus, Candida albicans.
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